PHARMACOLOGY

    The company offers a wide range of Pharmacology services including in-vitro & in-vivo efficacy studies in the therapeutic areas of Inflammation, Pain, Autoimmune disorders, Metabolic disorders (Diabetes- Type I & II), CNS disorders, Wound Healing, Hair growth, GI disorders etc. using relevant animal models.

AUTOIMMUNE DISORDERS/INFLAMMATION

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CANTACT DERMATITIS

  1. Oxazolone induced DTH mouse modele

RHEUMATOID ARTHRITIS

  1. Collagen induced arthritis mouse model
  2. Collagen-Ab induced arthritismouse model
  3. Freund’s Adjuvant induced arthritis mouse model

OSTEOARTHRITIS

  1. MIA (Monosodium Iodoacetate) model in rat and Guinea pig

PSORIASIS

  1. TPA induced psoriasis mouse model
  2. Imiquimod (IMQ) induced psoriasis mouse model

ULCERATIVE COLITIS

  1. DSS induced UC mouse model
  2. TNBS induced UC mouse model
  3. Oxazolone induced UC mouse model
  4. Acetic acid induced UC rat model
  5. Indomethacin-induced UC rabbit model

METABOLIC DISORDERS

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DIABETES

Type I Diabetes (IDDM)

  1. STZ induced diabetes
  2. Alloxan induced diabetes

OBESITY

  1. High- Fat Diet Induced Obesity in Mouse Model

HYPERLIPIDEMIA

  1. Triton X-100 induced hyperlipidemia in SD rats

TYPE 2 DIABETES (NIDDM)

  1. STZ-HFD induced diabetes
  2. Neonatal STZ induced type 2 diabetes
  3. Streptozotocin-nicotinamide induced type 2 diabetes

PAIN MODELS

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NEUROPATHIC PAIN

  1. Chronic Constriction Injury (CCI)- neuropathic pain
  2. Chemotherapy (Paclitaxel) induced neuropathic pain
  3. Streptozotocin (STZ)-induced diabetic neuropathy pain

INFLAMMATORY PAIN MODELS

  1. Carrageenan induced inflammatory pain model
  2. CFA induced inflammatory pain model

NOCICEPTIVE PAIN MODELS

  1. Hot Plate Test
  2. Tail Flick Test
  3. Tail Immersion Test
  4. Formalin induced Paw LickingTest
  5. Acetic Acid Writhing Test

CENTRAL NERVOUS SYSTEM DISORDERS

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ANTIDEPRESSANT ACTIVITY

  1. Forced Swim Test
  2. Tail Suspension Test
  3. Locomotor activity- Actophotometer test
  4. Open-field test

ANXIOLYTIC ACTIVITY

  1. Elevated Plus Maze test
  2. Light–dark box test
  3. Hole board test
  4. Marble-burying test

ANTI-CONVULSANT/ANTI-SEIZURE ACTIVITY

  1. Pentylenetetrazole (PTZ) induced seizures mouse model
  2. Isoniazid or isonicotinic hydrazide (INH)- induced convulsions mouse model
  3. Maximum electro shock (MES) induced convulsions mouse model

ANTI-PARKINSON DISEASE ACTIVITY

  1. 6-Hydroxydopamine hydrobromide (6-OHDA Hydrobromide) induced Parkinson mouse model
  2. Haloperidol Induced Catalepsy Test
  3. MPTP Mouse Model of Parkinson’s Disease
  4. Reserpine induced Parkinson’s Disease

NEUROMUSCULAR/MOTOR COORDINATION

  1. Rota rod test

LUNGS & LIVER DISORDERS

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LUNG DISEASES

PULMONARY FIBROSIS

  1. Bleomycin (BLM)-induced pulmonary fibrosis mouse model
  2. Lung Injury- LPS induced lung injury model

LIVER DISEASES

  1. CCL4 Liver Toxicity Rat Model
  2. Anti-TB Drug Induced Liver Toxicity Rat Model

WOUND HEALING ACTIVITY

  1. Excision wound model
  2. Burn wound model
  3. Incision wound model

HAIR GROWTH

  1. Hair Growth Effect on Balb/c Nude/C57BL/6 mice

GASTRO-INTESTINAL DISORDERS

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ANTIULCER ACTIVITY

  1. Pyloric Ligation Induced Gastric Ulceration
  2. Ethanol Induced Mucosal Damage in Rats
  3. Cysteamine Induced Duodenal Ulceration
  4. Indomethacin Induced Gastric Ulceration
  5. Cold Restraint Stress-Induced Ulcer
  6. Acetic Acid-Induced Chronic Ulcer


  7. GASTRIC EMPTYING TIME

    GASTROINTESTINAL TRANSIT

    CUSTOMIZED ANIMAL MODELS